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Phase 6: Real ProjectsModule 23 of 25

Biosignal Amplifier Front End

Real Project — a 3-lead ECG instrumentation amplifier design for a bedside patient monitor, with worked gain and CMRR calculations.

Biosignal Acquisition: ECG, EEG, EMG Fundamentals Guide ↗IEC 60601 Electrical Safety for Medical Devices Guide ↗Concept Explainer: ECG vs. EEG ↗
123Regulatory & Quality Foundations
45678Core Technical Disciplines
9101112Evidence, Software & Post-Market
13141516Applied Device Domains
171819Operations, Safety & Sustainability
202122📈24Real Projects
25Certification
🧪Next module · Module 24Sterilization Validation Protocol→
About this module

This project designs a 3-lead ECG front end for a bedside patient monitor, acquiring a surface ECG signal in the 0.5-4 mV amplitude range and feeding a 12-bit ADC with a 3.3V full-scale input, targeting the AAMI EC13/IEC 60601-2-27 monitoring-mode bandwidth of 0.5-40 Hz rather than the wider diagnostic-mode bandwidth a 12-lead cart requires.

It works through a worked instrumentation amplifier gain calculation and CMRR requirement, high-pass filter design for baseline wander rejection, low-pass filter design for anti-aliasing and EMG noise rejection, and a right-leg-drive circuit that improves common-mode rejection while limiting patient safety current — assembling the complete front end and directly applying the instrumentation amplifier principles built in Module 6 and the leakage current limits built in Module 18.

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